Gaceta medica de Mexico · 2003
[lymphatic Mapping and Sentinel Lymph Node Biopsy in patients with Breast Cancer ].
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Gallegos-Hernández José Francisco, Chávez-García Martha Alicia, Nájera Isaac, Ramírez-Ramírez Lourdes, Durán-Martínez Mario
Аннотация
UNLABELLED: Axillary lymphadenectomy is the standard of care in breast cancer patients. Lymphatic mapping has arisen as an alternative offering less morbidity.
OBJECTIVE: To determine the success rate of subareolar blue dye injection (SM) in sentinel node (SN) biopsy and its value in axillary staging.
METHODS: 62 stages I and II breast cancer patients without palpable axillary nodes received subareolar injection of blue dye; an intraoperative study of the SN was carried out. Axillary lymphadenectomy was carried out in all patients. Sensitivity, specificity, positive predictive value, and negative predictive value were measured.
RESULTS: In 58/62 patients (93.5%), SN was identified; 19/58(32%) patients had nodal metastases, 18 were identified in intraoperative study, and only one false negative; 12/18 patients showed metastasis in other axillary nodes (66%), in 6 (27%) the only metastasis site was SN. Sensitivity/specificity of the SN was 92.8 and 88.6%, respectively. Positive predictive value is 72.2% and negative predictive value is 97.5%
CONCLUSION: SAI of blue dye allows identification of SN in 93.5%; with high sensitivity. SN negative predictive value is 97.5% in this study.
OBJECTIVE: To determine the success rate of subareolar blue dye injection (SM) in sentinel node (SN) biopsy and its value in axillary staging.
METHODS: 62 stages I and II breast cancer patients without palpable axillary nodes received subareolar injection of blue dye; an intraoperative study of the SN was carried out. Axillary lymphadenectomy was carried out in all patients. Sensitivity, specificity, positive predictive value, and negative predictive value were measured.
RESULTS: In 58/62 patients (93.5%), SN was identified; 19/58(32%) patients had nodal metastases, 18 were identified in intraoperative study, and only one false negative; 12/18 patients showed metastasis in other axillary nodes (66%), in 6 (27%) the only metastasis site was SN. Sensitivity/specificity of the SN was 92.8 and 88.6%, respectively. Positive predictive value is 72.2% and negative predictive value is 97.5%
CONCLUSION: SAI of blue dye allows identification of SN in 93.5%; with high sensitivity. SN negative predictive value is 97.5% in this study.