Retinal cases & brief reports · 2016
PIMASERTIB AND SEROUS RETINAL DETACHMENTS.
Клинический случайСтатьяНазвание и аннотация: Перевод пока не подготовлен
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AlAli Alaa, Bushehri Ahmad, Park Jonathan C, Krema Hatem, Lam Wai-Ching
Аннотация
PURPOSE: To report a case of multifocal serous retinal detachments associated with pimasertib.
METHODS: The authors report a 26-year-old patient who developed bilateral multifocal serous retinal detachments appearing 2 days after starting pimasertib (as part of a clinical trial investigating its use in low-grade metastatic ovarian cancer) and rapidly resolving 3 days after stopping it.
CONCLUSION: The mechanism of MEK inhibitor induced visual toxicity remains unclear. The pathophysiology of multifocal serous retinal detachments as a complication of pimasertib is still poorly understood.
METHODS: The authors report a 26-year-old patient who developed bilateral multifocal serous retinal detachments appearing 2 days after starting pimasertib (as part of a clinical trial investigating its use in low-grade metastatic ovarian cancer) and rapidly resolving 3 days after stopping it.
CONCLUSION: The mechanism of MEK inhibitor induced visual toxicity remains unclear. The pathophysiology of multifocal serous retinal detachments as a complication of pimasertib is still poorly understood.