A protective maternal nutrient concomitant intake associated with acute leukemia might be modified by sex, in children under 2 years.
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Mérida-Ortega Ángel, Pérez-Saldivar María Luisa, Espinoza-Hernández Laura E, Dorantes-Acosta Elisa M, Torres-Nava José Refugio, Solís-Labastida Karina A, Paredes-Aguilera Rogelio, Velázquez-Aviña Martha M, Espinosa-Elizondo Rosa Martha, Miranda-Madrazo M Raquel, González-Ávila Ana Itamar, Rodríguez-Villalobos Luis Rodolfo, Dosta-Herrera Juan José, Mondragón-García Javier A, Castañeda-Echevarría Alejandro, López-Caballero M Guadalupe, Martínez-Silva Sofía I, Rivera-González Juan, Hernández-Pineda Norma Angélica, Flores-Botello Jesús, Pérez-Gómez Jessica Arleet, Rodríguez-Vázquez María Adriana, Torres-Valle Delfino, Olvera-Durán Jaime Ángel, Martínez-Ríos Annel, García-Cortés Luis R, Almeida-Hernández Carolina, Flores-Lujano Janet, Núñez-Enríquez Juan Carlos, Mata-Rocha Minerva, Rosas-Vargas Haydeé, Duarte-Rodríguez David Aldebarán, Jiménez-Morales Silvia, Mejía-Arangure Juan Manuel, López-Carrillo Lizbeth
Аннотация
METHODS: We conducted a study of 110 cases of AL and 252 hospital-based controls in the Mexico City Metropolitan area from 2010 to 2019. We obtained information on maternal intake of 32 nutrients by a food frequency questionnaire and used weighted quantile sum regression to identify nutrient concomitant intakes.
RESULTS: We found a concomitant intake of nutrients negatively associated with AL (OR 0.17; CI95% 0.03,0.88) only among girls; and we did not find a nutrient concomitant intake positively associated with AL.
DISCUSSION: This is the first study that suggests nutrients that have been individually associated with AL are not necessarily the same in the presence of other nutrients (concomitant intake); as well as that maternal diet might reduce AL risk only in girls.