Reversal of optic disc topography in patients with glaucomatocyclitic crisis after remission of attack.

PURPOSE: The authors investigate change in optic disc topography after reduction of intraocular pressure (IOP) in patients with glaucomatocyclitic crisis.

METHODS

During the attack of elevated IOP and after remission six eyes of six consecutive patients (46.3 +/- 12.7 years of age, 6 men) underwent optic disc imaging using confocal scanning laser tomography. For each imaging of one eye, a mean topograph was acquired after triple measurements with 15 degrees of field. Topical 0.5% timolol maleate and 1% prednisolone acetate with or without oral carbonic anhydrase inhibitor were administered after optic disc topography during the attack. The average time interval between the imaging during attack and after remission was 38.5 days (range, 21-87 days).

RESULTS

Mean IOP during the attack and after remission, and percent decrease in IOP were: 43.3 +/- 10.4 mmHg, 13.5 +/- 6.5 mmHg, and 69.4 +/- 10.2%, respectively. Significant decreases in cup area, cup volume, cup/disc area ratio, and mean cup depth and significant increases in rim area and rim volume were observed after IOP reduction (Wilcoxon signed rank test). Significant associations were found between percent decrease in IOP and percent decrease in cup volume and percent increase in rim area and rim volume.

CONCLUSION

In patients experiencing glaucomatocyclitic crisis, reversal of optic disc topography were associated with reduction of IOP.