[Treatment resistant schizophrenia, residual subtype: symptom improvement after additional treatment with amisulpride].

BACKGROUND

Therapy resistant, severe residual schizophrenia poses major challenges for the psychiatric pharmacological treatment.

METHOD: We report about a 44-year old schizophrenic male who has been detained in a closed forensic ward for 10 years, following a conviction in one manslaughter case. Despite various pharmacological treatment efforts severe residual schizophrenia remained.

RESULT: Adding Amisulpride to the ongoing treatment with Olanzapine achieved a noticeable improvement of symptoms, resulting in the possibility of relaxing imprisonment conditions.

CONCLUSION

A combination of Amisulpride and Olanzapine seems to be effective in treating severe residual schizophrenia.