[The chronobiological characteristics of the antistressor action of anxiolytic agents].

Agents with anxiolytic properties, namely, the tranquilizer diazepam (0.1 mg/kg), melatonin a hormone secreted by the pineal gland (0.1 mg/kg), and the beta-adrenergic blocker anapriline (5 mg/kg), remove in a similar manner stress-induced dysrhythmia in rats. Under their effect the circadian rhythm of motor activity is normalized and adaptation shifts in the time dynamics of forced swimming are encountered.