Annales d'endocrinologie · 2009
F-18 FDG PET detection of a medullary thyroid carcinoma in a patient with metastatic colonic cancer; literature review.
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Cohen R, Bihan H, des Guetz G, Wind P, Martin A
Аннотация
OBJECTIVE: We report a case of a medullary thyroid carcinoma discovered by F-18 fluorodeoxyglucose-positron emission tomography (F-18 FDG PET).
PATIENT AND METHODS: A 73-year-old man with a history of surgical removal of sigmoid colon cancer underwent F-18 FDG PET to search for distant metastases and / or local recurrence because of elevated CEA level and new episode of occlusion. F-18 FDG PET images showed increased focal FDG uptake in the right lobe of the thyroid. Thyroid ultrasound showed one thyroid nodule in each lobe.
RESULTS: The fine needle aspiration result was suspicious and calcitonin level was elevated. The subject underwent thyroidectomy without lymph node dissection. The pathology showed a 14 mm medullary thyroid carcinoma. There was no germline mutation of RET.
CONCLUSIONS: F-18 FDG PET can detect primitive or secondary malignant thyroid tumors. Thus, thyroid incidentaloma revealed by 18 FDG PET uptake always necessitates careful evaluation.
PATIENT AND METHODS: A 73-year-old man with a history of surgical removal of sigmoid colon cancer underwent F-18 FDG PET to search for distant metastases and / or local recurrence because of elevated CEA level and new episode of occlusion. F-18 FDG PET images showed increased focal FDG uptake in the right lobe of the thyroid. Thyroid ultrasound showed one thyroid nodule in each lobe.
RESULTS: The fine needle aspiration result was suspicious and calcitonin level was elevated. The subject underwent thyroidectomy without lymph node dissection. The pathology showed a 14 mm medullary thyroid carcinoma. There was no germline mutation of RET.
CONCLUSIONS: F-18 FDG PET can detect primitive or secondary malignant thyroid tumors. Thus, thyroid incidentaloma revealed by 18 FDG PET uptake always necessitates careful evaluation.