International journal of pediatric otorhinolaryngology · 2019
Characterization of acute otitis media otopathogens before the introduction of the pneumococcal conjugated vaccine into the national immunization program in Poland.
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Górska-Kot Aneta, Greenberg David, Gastoł Karolina, Zieliński Adam, Givon-Lavi Noga
Аннотация
BACKGROUND: Bacterial etiologic data for acute otitis media (AOM) otopathogens in Poland are scarce. The aim of this study was to determine the bacterial etiology and antibiotic susceptibility patterns of otopathogens in children prior to the introduction of the pneumococcal conjugated vaccine (PCV) into the national immunization program (NIP) in Poland.
METHODS: Demographic and laboratory data of children < 5 years old who underwent tympanocentesis due to AOM in Nieklanska Hospital Warsaw between 2010 and 2016, were collected. All middle ear fluids (MEF) cultures were processed at the hospital according to conventional culture methods.
RESULTS: Out of 940 MEF cultures, 407 (43.3%) were positive for 419 isolates. The most common etiologies of positive cultures were: S. pneumonaie, nontypeable H. infuenzae (NTHi), and S. pyogenes. Children aged 12-23 months had significantly more S. pneumoniae and NTHi positive cultures than children <12 months of age. S. pneumoniae isolates non-susceptible to penicillin, erythromycin, and clindamycin, declined over the study period (2010-2016).
CONCLUSIONS: This is the largest dataset of MEF isolates from AOM patients in Poland, collected during the pre-PCV period. These data can help determine the appropriate treatment for AOM patients and can serve as a baseline for the period before the introduction of PCV to the NIP in Poland.
METHODS: Demographic and laboratory data of children < 5 years old who underwent tympanocentesis due to AOM in Nieklanska Hospital Warsaw between 2010 and 2016, were collected. All middle ear fluids (MEF) cultures were processed at the hospital according to conventional culture methods.
RESULTS: Out of 940 MEF cultures, 407 (43.3%) were positive for 419 isolates. The most common etiologies of positive cultures were: S. pneumonaie, nontypeable H. infuenzae (NTHi), and S. pyogenes. Children aged 12-23 months had significantly more S. pneumoniae and NTHi positive cultures than children <12 months of age. S. pneumoniae isolates non-susceptible to penicillin, erythromycin, and clindamycin, declined over the study period (2010-2016).
CONCLUSIONS: This is the largest dataset of MEF isolates from AOM patients in Poland, collected during the pre-PCV period. These data can help determine the appropriate treatment for AOM patients and can serve as a baseline for the period before the introduction of PCV to the NIP in Poland.