Medical physics · 2018
Three-dimensional-printed vaginal applicators for electronic brachytherapy of endometrial cancers.
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Lee Ju Hyuk, Kim Hyun Nam, Lim Hyung San, Cho Sung Oh
Аннотация
PURPOSE: Vaginal applicators for a novel miniature x-ray tube were developed using three-dimensional (3D) printing to be used in brachytherapy of endometrial cancers.
METHODS: Cylindrical vaginal applicators with various diameters, lengths, and infill percentages (IFPs) were fabricated using a 3D printer. X-ray dose distributions and depth-dose profiles were calculated using a Monte Carlo simulation. The performances of the applicators were evaluated by measuring and analyzing the dosimetric characteristics of x rays generated from the miniature x-ray tube equipped with the applicators.
RESULTS: Quite uniform dose distributions around the applicators were achieved by optimizing the dwell positions and the dwell times of the miniature x-ray tube inside the applicators. In addition, identical absolute dose and depth-dose profiles were obtained through the control of the IFP values even though different-sized applicators are used.
CONCLUSION: The presented 3D printing technique provides an efficient approach to provide vaginal applicators with optimal IFPs that allow consistent treatment time for patients of varying vaginal canal size.
METHODS: Cylindrical vaginal applicators with various diameters, lengths, and infill percentages (IFPs) were fabricated using a 3D printer. X-ray dose distributions and depth-dose profiles were calculated using a Monte Carlo simulation. The performances of the applicators were evaluated by measuring and analyzing the dosimetric characteristics of x rays generated from the miniature x-ray tube equipped with the applicators.
RESULTS: Quite uniform dose distributions around the applicators were achieved by optimizing the dwell positions and the dwell times of the miniature x-ray tube inside the applicators. In addition, identical absolute dose and depth-dose profiles were obtained through the control of the IFP values even though different-sized applicators are used.
CONCLUSION: The presented 3D printing technique provides an efficient approach to provide vaginal applicators with optimal IFPs that allow consistent treatment time for patients of varying vaginal canal size.