Primary Extrapulmonary Rifampicin Mono-Resistant Tuberculosis (TB) of the Endometrium in a Sexually Inactive 20-Year-Old Indian Female: A Very Rare Case.

Female genital tract tuberculosis (TB) is less frequently reported, even in endemic countries. Often, the diagnosis is incidental and is seen with the involvement of pulmonary or extrapulmonary sites. Isolated female genital tract TB is quite rare, and cases of primary extrapulmonary rifampicin mono-resistant TB of the genital tract are rarest of the rare. In this case, a 20-year-old sexually inactive female with no history of TB presented with complaints of pain in her abdomen for past two months and absence of menstrual cycles since two years and was later diagnosed based on hysteroscopy, endometrial biopsy, and cartridge-based nucleic acid amplification test (CBNAAT) with primary extrapulmonary rifampicin mono-resistant TB of the endometrium. She was started on a WHO-recommended rifampicin mono-resistant TB regimen for 24 months but was ultimately lost to follow-up.