Future oncology (London, England) · 2019
I-O Optimise: a novel multinational real-world research platform in thoracic malignancies.
СтатьяМногоцентровое исследованиеНазвание и аннотация: Перевод пока не подготовлен
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Ekman Simon, Griesinger Frank, Baas Paul, Chao David, Chouaid Christos, O'Donnell John C, Penrod John R, Daumont Melinda, Lacoin Laure, McKenney Alexia, Khovratovich Masha, Munro Robin Ej, Durand-Zaleski Isabelle, Johnsen Søren Paaske
Аннотация
Aim: To describe I-O Optimise, a multinational program providing real-world insights into lung cancer management. Materials & methods: Real-world data source selection for I-O Optimise followed a structured approach focused on population coverage, key variable capture, continuous/consistent data availability, record duration and data latency, and database expertise. Results: As of 31 October 2018, seven real-world data sources were included in I-O Optimise, providing data on characteristics, treatment patterns and clinical outcomes from more than 45,000 patients/year with non-small-cell lung cancer, small-cell lung cancer and mesothelioma across Denmark, Norway, Portugal, Spain, Sweden and the UK. Conclusion: The ongoing I-O Optimise initiative has the potential to provide a broad, robust and dynamic research platform to continually address numerous research objectives in the lung cancer arena.