Skin appendage disorders · 2026
The Value of Trichoscopy and Histopathology in the Diagnosis of Post-COVID-19 Telogen Effluvium.
СтатьяНазвание и аннотация: Перевод в очереди
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Martínez-Velasco María Abril, Thompson Curtis, Tosti Antonella, Olivas-Altamirano Marla Daniela, Ramírez-Marín Hassiel Aurelio
Аннотация
INTRODUCTION: Telogen effluvium (TE) is a recognized sequel of COVID-19 infection, often exhibiting an accelerated onset that suggests a pathomechanism distinct from classical TE. This study aims to define the unique trichoscopic and histopathological features of post-COVID-19 TE and to correlate these novel findings with prior systemic disease severity.
METHODS: Trichoscopy images and pathology specimens of 13 patients (12 women, 1 man; mean age 46.2 years) who developed TE after PCR-confirmed COVID-19 infection were retrospectively reviewed. Statistical analysis correlated trichoscopic findings with the need for supplementary oxygen during acute infection.
RESULTS: Trichoscopy showed thick, livedoid arborizing vessels in most cases, with giant serpiginous vessels in 38% of patients. The presence of giant vessels showed a strong statistical correlation with the requirement of supplementary oxygen during hospitalization (p = 0.001). Histopathology confirmed a catagen/telogen shift and consistently revealed a superficial perivascular and perifollicular lymphocytic infiltrate in all cases.
CONCLUSION: Vascular patterns can distinguish post-COVID-19 TE. The perifollicular lymphocytic infiltrate supports a direct viral or localized immune-mediated insult.
METHODS: Trichoscopy images and pathology specimens of 13 patients (12 women, 1 man; mean age 46.2 years) who developed TE after PCR-confirmed COVID-19 infection were retrospectively reviewed. Statistical analysis correlated trichoscopic findings with the need for supplementary oxygen during acute infection.
RESULTS: Trichoscopy showed thick, livedoid arborizing vessels in most cases, with giant serpiginous vessels in 38% of patients. The presence of giant vessels showed a strong statistical correlation with the requirement of supplementary oxygen during hospitalization (p = 0.001). Histopathology confirmed a catagen/telogen shift and consistently revealed a superficial perivascular and perifollicular lymphocytic infiltrate in all cases.
CONCLUSION: Vascular patterns can distinguish post-COVID-19 TE. The perifollicular lymphocytic infiltrate supports a direct viral or localized immune-mediated insult.