Taiwan journal of ophthalmology · 2022
A case of aseptic bilateral cavernous sinus thrombosis following a recent inactivated SARS-CoV-2 vaccination.
Клинический случайСтатьяНазвание и аннотация: Перевод пока не подготовлен
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Nusanti Syntia, Putera Ikhwanuliman, Sidik M, Edwar Lukman, Koesnoe Sukamto, Rachman Andhika, Kurniawan Mohammad, Edi Tarigan Tri Juli, Yunus Reyhan Eddy, Saraswati Indah, Zoraida Soraya Siti Halida, Pratomo Tiara Grevillea, Nora Rina La Distia
Аннотация
This case report aims to describe the first report of bilateral aseptic cavernous sinus thrombosis (CST) with a recent history of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccination. A 50-year-old woman presented with bilateral proptosis, decreased vision, and ophthalmoplegia 16 days following CoronaVac® vaccine. The visual acuity of the left eye was 20/150, while the right eye was no light perception with a hyperemic optic nerve head. She had a history of hyperthyroidism and currently on warfarin consumption. Laboratory results depicted elevated free T4, free T3, international normalized ratio, and low protein S and C. Magnetic resonance imaging showed bilateral CST, and high-dose methylprednisolone along with fondaparinux was given. The symptoms were significantly resolved, with the visual acuity of the left eye being improved to 20/20 but not the right eye. Bilateral CST has not been previously reported following inactivated SARS-CoV-2 vaccination. The underlying systemic conditions should be taken into consideration for the possibility of the inactivated SARS-CoV-2 vaccine-related event.