Medicine · 2019
Sixteen-and-a-half syndrome with metastatic pons tumor: A case report.
Клинический случайСтатьяНазвание и аннотация: Перевод в очереди
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Choi Shin-Myeong, Kim Tae Gi, Chung Junkyu, Joo Jin-Ho, Park In-Ki, Moon Sang Woong, Shin Jae-Ho
Аннотация
RATIONALE: One-and-a-half syndrome (OAAH) is characterized as the combination of ipsilateral horizontal gaze palsy and internuclear ophthalmoplegia. OAAH syndrome accompanied with 7th and 8th cranial nerve palsy is called 16-and-a-half syndrome. We aimed to report the case of 16-and-a-half syndrome with metastatic pons tumor.
PATIENT CONCERNS: A 57-year-old male diagnosed with nonsmall-cell lung cancer (NSCLC) with brain metastasis occurring 15 months ago was referred to our clinic with the chief complaint of horizontal diplopia and right gaze palsy.
DIAGNOSIS: According to the patient symptom, ocular examination, and radiographic findings, he was diagnosed as 16-and-a-half syndrome which was caused by brain tumor metastasis from NSCLC.
INTERVENTIONS: We referred him to hemato-oncology department and he was treated with radiation and supportive therapy.
OUTCOMES: Unfortunately, the patient passed away 1 month later without improvement of ophthalmoplegia.
LESSONS: The clinical findings of our case indicate 16-and-a-half syndrome caused by brain tumor metastasis from NSCLC, which to our knowledge has not been previously reported. The case highlights a rare cause of OAAH spectrum disease and the importance of a systemic work-up including associated neurologic symptoms and brain imaging in patients with horizontal gaze palsy.
PATIENT CONCERNS: A 57-year-old male diagnosed with nonsmall-cell lung cancer (NSCLC) with brain metastasis occurring 15 months ago was referred to our clinic with the chief complaint of horizontal diplopia and right gaze palsy.
DIAGNOSIS: According to the patient symptom, ocular examination, and radiographic findings, he was diagnosed as 16-and-a-half syndrome which was caused by brain tumor metastasis from NSCLC.
INTERVENTIONS: We referred him to hemato-oncology department and he was treated with radiation and supportive therapy.
OUTCOMES: Unfortunately, the patient passed away 1 month later without improvement of ophthalmoplegia.
LESSONS: The clinical findings of our case indicate 16-and-a-half syndrome caused by brain tumor metastasis from NSCLC, which to our knowledge has not been previously reported. The case highlights a rare cause of OAAH spectrum disease and the importance of a systemic work-up including associated neurologic symptoms and brain imaging in patients with horizontal gaze palsy.