[A Case of Apocrine Carcinoma of the Breast with Complete Response to Chemotherapy for Local Recurrence after 13 Years of Surgery].

The patient is a 46-year-old woman who previously underwent a partial mastectomy with sentinel lymph node biopsy for a 5.6 cm diameter noninvasive breast apocrine carcinoma in the upper, inner quadrant right breast at age 33. Thirteen years later, a 2.1 cm diameter tumor appeared in the same area, and core needle biopsy examination revealed invasive apocrine carcinoma(ER[-], PR[-], HER2[+]). Without distant metastasis, the patient received doxorubicin plus cyclophosphamide( AC)therapy followed by trastuzumab, pertuzumab, docetaxel(HPD)therapy as neoadjuvant chemotherapy. Subseqently, the tumor disappeared clinically. Mastectomy was performed, and complete response was confirmed pathologically.