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DOI 10.19540/j.cnki.cjcmm.2017.0046

Медицинская библиотека · Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica · 2017

[Lanqin oral liquid for the treatment of chronic pharyngitis:systematic review and Meta-analysis of randomized clinical trials].

Li Na, Yang Feng-Wen, Lu Zhong-Ying, Zhang Dong, Liu Chun-Xiang, Zheng Wen-Ke

СтатьяМетаанализСистематический обзорПеревод в очереди

Аннотация

To systematically assess the effectiveness and safety of lanqin oral liquid for the treatment of chronic pharyngitis. Databases including PubMed, Embase, The Cochrane Library, SinoMed, CNKI, VIP and Wanfang Data were electronically searched in March 2017 for randomized controlled trials(RCTs) on Lanqin oral liquid for the treatment of chronic pharyngitis. Two authors independently screened literature, extracted data, and assessed the risk of bias of included studies. Then, meta-analysis was performed by RevMan 5.3 software. Thirteen RCTs were included with a total of 1 642 patients. The results of meta-analysis showed that the efficiency of lanqin oral liquid were significantly higher than those of conventional therapy or other treatments; Besides, lanqin oral liquid could significantly increase the amount of IL-2 further more, lanqin oral liquid could significantly reduce the amount of TNF-α. Safety of lanqin oral liquid was not concerned by any RCT. Current evidence indicates that the efficiency of lanqin oral liquid was better than conventional therapy or other treatments. Due to the poor quality of the included studies, the above conclusion should be verified by more RCTs of high quality.

Для цитирования: Li Na, Yang Feng-Wen, Lu Zhong-Ying, Zhang Dong, Liu Chun-Xiang, Zheng Wen-Ke. [Lanqin oral liquid for the treatment of chronic pharyngitis:systematic review and Meta-analysis of randomized clinical trials].. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2017. DOI: 10.19540/j.cnki.cjcmm.2017.0046.

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