Head & neck · 2014
Prognostic quality of the Union Internationale Contre le Cancer/American Joint Committee on Cancer TNM classification, 7th edition, for cancer of the maxillary sinus.
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Kreppel Matthias, Amir Manawi Nilofar-Natalie, Scheer Martin, Nickenig Hans-Joachim, Rothamel Daniel, Dreiseidler Timo, Drebber Uta, Zinser Max, Zöller Joachim E, Guntinas-Lichius Orlando, Preuss Simon Florian
Аннотация
BACKGROUND: Carcinomas of the maxillary sinus are classified according to the Union Internationale Contre le Cancer (UICC)/American Joint Committee on Cancer (AJCC) TNM classification. The purpose of this study was to assess the prognostic significance of the UICC/AJCC TNM classification seventh edition, which was introduced in 2010.
METHODS: One hundred thirteen patients with malignant tumors of the maxillary sinus were included in this study. The prognostic impact of the TNM classification and the UICC/AJCC seventh edition's stage grouping were analyzed in univariate and multivariate analysis.
RESULTS: The UICC/AJCC stage grouping, the T classification, and the N classification had a significant impact on overall survival (OS) in univariate analysis (p < .05). No significant differences were observed between the groups T4a and T4b (p = .109). In multivariate analysis, the UICC/AJCC stage grouping (p = .031), the N classification (p = .014), and age (p < .001) had a significant impact on OS.
CONCLUSION: Although UICC/AJCC stage grouping and the N classification provided a significant prediction of OS in univariate and multivariate analysis, T classification only influenced OS in univariate analysis.
METHODS: One hundred thirteen patients with malignant tumors of the maxillary sinus were included in this study. The prognostic impact of the TNM classification and the UICC/AJCC seventh edition's stage grouping were analyzed in univariate and multivariate analysis.
RESULTS: The UICC/AJCC stage grouping, the T classification, and the N classification had a significant impact on overall survival (OS) in univariate analysis (p < .05). No significant differences were observed between the groups T4a and T4b (p = .109). In multivariate analysis, the UICC/AJCC stage grouping (p = .031), the N classification (p = .014), and age (p < .001) had a significant impact on OS.
CONCLUSION: Although UICC/AJCC stage grouping and the N classification provided a significant prediction of OS in univariate and multivariate analysis, T classification only influenced OS in univariate analysis.
Предметные рубрики MeSH
AdultAge FactorsAgedAnalysis of VarianceCause of DeathCohort StudiesCombined Modality TherapyDisease-Free SurvivalFemaleHumansMaleMaxillary Sinus NeoplasmsMiddle AgedMultivariate AnalysisNeoplasm InvasivenessNeoplasm StagingPrognosisProportional Hazards ModelsQuality ControlRetrospective StudiesSex FactorsSocieties, MedicalStatistics, NonparametricSurvival AnalysisTreatment OutcomeUnited States