Papillomavirus research (Amsterdam, Netherlands) · 2017
Acceptability of cervical cancer screening using visual inspection among women attending a childhood immunization clinic in Uganda.
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Li Meng, Nyabigambo Agnes, Navvuga Patricia, Nuwamanya Elly, Nuwasiima Afra, Kaganda Paschal, Asiimwe Francis T, Vodicka Elisabeth, Mugisha Noleb M, Mukose Aggrey, Kwesiga Doris K, Lubinga Solomon J, Garrison Louis P, Babigumira Joseph B
Аннотация
OBJECTIVE: To evaluate the acceptability and performance of cervical cancer (CC) screening using visual inspection with acetic acid (VIA) integrated into a rural immunization clinic in Uganda.
METHODS/MATERIALS: We conducted a cross-sectional pilot study in rural Uganda. We explored associations between women's characteristics and acceptance of VIA testing. We collected samples for Papanicolaou (Pap) smear testing in a random subset of women and used results from this test as a comparator for assessing VIA performance.
RESULTS: We enrolled 625 women of whom 571 (91.4%) accepted and 54 (8.6%) refused CC screening. In the univariate model, age (Odds Ratio (OR)=1.10; p-value<0.001) and employment status (OR 2.00; p-value=0.019) were significantly associated with acceptance of VIA screening. In the multivariate model, no characteristic was independently associated with acceptance of VIA screening after adjusting for other factors. Compared to reference Pap smear, CC screening with VIA had a sensitivity of 50% and a specificity of 97.7%.
CONCLUSIONS: CC screening with VIA is highly acceptable in the setting of rural immunization clinics in Uganda. Studies to assess which screening method would be the most effective and cost-effective are needed before stakeholders can consider adopting screening programs at scale.
METHODS/MATERIALS: We conducted a cross-sectional pilot study in rural Uganda. We explored associations between women's characteristics and acceptance of VIA testing. We collected samples for Papanicolaou (Pap) smear testing in a random subset of women and used results from this test as a comparator for assessing VIA performance.
RESULTS: We enrolled 625 women of whom 571 (91.4%) accepted and 54 (8.6%) refused CC screening. In the univariate model, age (Odds Ratio (OR)=1.10; p-value<0.001) and employment status (OR 2.00; p-value=0.019) were significantly associated with acceptance of VIA screening. In the multivariate model, no characteristic was independently associated with acceptance of VIA screening after adjusting for other factors. Compared to reference Pap smear, CC screening with VIA had a sensitivity of 50% and a specificity of 97.7%.
CONCLUSIONS: CC screening with VIA is highly acceptable in the setting of rural immunization clinics in Uganda. Studies to assess which screening method would be the most effective and cost-effective are needed before stakeholders can consider adopting screening programs at scale.
Предметные рубрики MeSH
AdultAmbulatory Care FacilitiesColposcopyCross-Sectional StudiesEarly Detection of CancerFemaleHumansImmunizationMass ScreeningPapanicolaou TestPapillomavirus InfectionsPatient Acceptance of Health CarePilot ProjectsPregnancySensitivity and SpecificityUgandaUterine Cervical NeoplasmsVaginal SmearsVisual Fields