International journal of dermatology · 2015
Melanoma of the lower extremities: foot site is an independent risk factor for clinical outcome.
СтатьяНазвание и аннотация: Перевод пока не подготовлен
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Sanlorenzo Martina, Osella-Abate Simona, Ribero Simone, Marenco Federica, Nardò Tiziana, Fierro Maria Teresa, Novelli Mauro, Cervetti Ornella, Bernengo Maria Grazia, Quaglino Pietro
Аннотация
BACKGROUND: Despite the better prognosis of melanomas localized on lower extremities, some studies have suggested that melanomas on the foot are related to a poorer survival and should be considered separately.
OBJECTIVE: To review our case series of cutaneous melanomas on the lower extremities and to analyze the clinicopathological association, time course, types of progression, and survival differences.
METHODS: We included 1671 patients (stage 0-II) with a cutaneous melanoma on the lower extremities (subungual melanomas were excluded). Of these, 327 were localized on the foot. Multivariate analyses were performed to evaluate disease-specific survival and disease-free interval.
RESULTS: Distribution of known prognostic factors and patterns of progression of foot and leg melanoma differ across genders. The foot site was confirmed as a negative independent prognostic factor on disease-specific survival and disease-free interval.
CONCLUSION: Foot melanoma could represent a particular subgroup, which could require specific management in the future.
OBJECTIVE: To review our case series of cutaneous melanomas on the lower extremities and to analyze the clinicopathological association, time course, types of progression, and survival differences.
METHODS: We included 1671 patients (stage 0-II) with a cutaneous melanoma on the lower extremities (subungual melanomas were excluded). Of these, 327 were localized on the foot. Multivariate analyses were performed to evaluate disease-specific survival and disease-free interval.
RESULTS: Distribution of known prognostic factors and patterns of progression of foot and leg melanoma differ across genders. The foot site was confirmed as a negative independent prognostic factor on disease-specific survival and disease-free interval.
CONCLUSION: Foot melanoma could represent a particular subgroup, which could require specific management in the future.
Предметные рубрики MeSH
AdultAge FactorsAgedAged, 80 and overAnalysis of VarianceDatabases, FactualDisease-Free SurvivalFemaleFootHumansLegLymph NodesMaleMelanomaMiddle AgedMultivariate AnalysisNeoplasm InvasivenessNeoplasm StagingPrognosisRetrospective StudiesRisk AssessmentSex FactorsSkin NeoplasmsSurvival AnalysisYoung AdultCutaneous Malignant Melanoma