Premycotic poikiloderma, mycosis fungoides and cutaneous squamous cell carcinoma. Two cases and a discussion of their relevance.

Two patients with premycotic poikiloderma developed one squamous cell carcinoma each. A review of the literature reveals 28 reported cases of this association, but in 26 of these the patient had been exposed to carcinogens. Our patients had no history of exposure to carcinogenic agents. In both our cases, the squamous carcinomas behaved aggressively. The possible relationship with the poikiloderma is discussed.