The Journal of reproductive medicine · 2007
Benign lipoblastomalike tumor of the vulva: report of a case affecting a young patient.
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Atallah David, Rouzier Roman, Chamoun Marie Laurence, Mansour Fersan, Nabaa Toufic, Chababi Mirna, Duvillard Pierre, Chahine Georges
Аннотация
BACKGROUND: Mesenchymal vulvar tumors are rare, and a benign lipoblastomalike tumor may be confused with malignancy.
CASE: A 15-year-old patient consulted for a right labium tumefaction measuring 15 cm. After excision, histologic examination revealed a well-circumscribed and lobulated tumor. The lobules were composed of slender spindle cells showing slightly eosinophilic cytoplasm with indistinct boundaries, uniform nuclei with finely granular chromatin and no nucleoli. Scattered Signet-ring-type lipoblasts were observed. The background was myxoid, with a "chickenwire" capillary vascular network mimicking a myxoid liposarcoma. No mitotic figures, necrosis or pleomorphism was noted.
CONCLUSION: This mesenchymal tumor had adipocytic differentiation and no patent sign of malignancy, akin to infantile lipoblastoma. Because of the benign behavior of this tumor, complete excision without radiation is recommended.
CASE: A 15-year-old patient consulted for a right labium tumefaction measuring 15 cm. After excision, histologic examination revealed a well-circumscribed and lobulated tumor. The lobules were composed of slender spindle cells showing slightly eosinophilic cytoplasm with indistinct boundaries, uniform nuclei with finely granular chromatin and no nucleoli. Scattered Signet-ring-type lipoblasts were observed. The background was myxoid, with a "chickenwire" capillary vascular network mimicking a myxoid liposarcoma. No mitotic figures, necrosis or pleomorphism was noted.
CONCLUSION: This mesenchymal tumor had adipocytic differentiation and no patent sign of malignancy, akin to infantile lipoblastoma. Because of the benign behavior of this tumor, complete excision without radiation is recommended.