[Preoperative sonovue contrast color Doppler in patients with cervical cancer. Preliminary report].

OBJECTIVE

Angiogenesis has gained much attention in oncology in recent years. The purpose of this pilot study was to describe the preoperative sonographic patterns of SonoVue Contrast-Doppler ultrasound and the standard Color Dopper ultrasound of cervical cancer tumor angiogenesis.

MATERIALS AND

METHODS

This is a prospective observational study. The study included fifteen patients with proven cervical cancer.

RESULTS

Contrast Doppler US after the SonoVue injection gave a good picture of the intense intralesional tumor angiogenesis. Of the 15 patients with FIGO stage lb1 Contrast-sonography showed 12 patients stage Ib1, 1-stage Ib2, 1-stage IIb and 1-stage Iva at final diagnosis.

CONCLUSIONS

SonoVue Contrast Doppler Ultrasound gave a better definition of the margins of the neoplastic lesions in the cervical cancer Because contrast agents increase the sensitivity of detection of parametrial invasion and lymph node metastases, they could pay an important role in the evaluation of uterine cervical cancer