Orbit (Amsterdam, Netherlands) · 2026
CT-guided biopsy with fine-needle via the anterior approach in the diagnosis of orbital lymphoma: a case series.
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Liu Shuyi, Mei Yingxue, Zhou Ziyue, Kikkawa Don O, Lu Wei
Аннотация
BACKGROUND: To evaluate the clinical efficacy of CT-guided biopsy via the anterior approach in diagnosing orbital lymphoma.
METHODS: From November 2018 to July 2021, 11 patients suspected of having orbital lymphoma based on imaging were selected from the Second Hospital of Dalian Medical University. Each patient underwent a CT-guided biopsy using a semi-automatic 18 G needle. Biopsies were performed under local anesthesia, and the obtained tissue samples were analyzed for a definitive diagnosis.
RESULTS: Adequate tissue samples were successfully obtained in all 11 cases. Of these, 7 patients (63.6%) were diagnosed with lymphoma, including subtypes such as extranodal marginal zone B-cell lymphoma, diffuse large B-cell lymphoma, and mantle cell lymphoma. Other diagnoses included IgG4-related ophthalmic disease (9.1%), and chronic inflammatory hyperplasia (27.3%). A small subcutaneous hematoma occurred in 1 patient (9.1%), which resolved without additional intervention.
CONCLUSION: CT-guided biopsy via the anterior approach is an effective technique for diagnosing orbital lymphoma. It is cost-effective, minimally invasive, allows for quicker recovery, and is associated with fewer adverse events compared to traditional surgical biopsy.
METHODS: From November 2018 to July 2021, 11 patients suspected of having orbital lymphoma based on imaging were selected from the Second Hospital of Dalian Medical University. Each patient underwent a CT-guided biopsy using a semi-automatic 18 G needle. Biopsies were performed under local anesthesia, and the obtained tissue samples were analyzed for a definitive diagnosis.
RESULTS: Adequate tissue samples were successfully obtained in all 11 cases. Of these, 7 patients (63.6%) were diagnosed with lymphoma, including subtypes such as extranodal marginal zone B-cell lymphoma, diffuse large B-cell lymphoma, and mantle cell lymphoma. Other diagnoses included IgG4-related ophthalmic disease (9.1%), and chronic inflammatory hyperplasia (27.3%). A small subcutaneous hematoma occurred in 1 patient (9.1%), which resolved without additional intervention.
CONCLUSION: CT-guided biopsy via the anterior approach is an effective technique for diagnosing orbital lymphoma. It is cost-effective, minimally invasive, allows for quicker recovery, and is associated with fewer adverse events compared to traditional surgical biopsy.