CT-guided biopsy with fine-needle via the anterior approach in the diagnosis of orbital lymphoma: a case series.

BACKGROUND

To evaluate the clinical efficacy of CT-guided biopsy via the anterior approach in diagnosing orbital lymphoma.

METHODS

From November 2018 to July 2021, 11 patients suspected of having orbital lymphoma based on imaging were selected from the Second Hospital of Dalian Medical University. Each patient underwent a CT-guided biopsy using a semi-automatic 18 G needle. Biopsies were performed under local anesthesia, and the obtained tissue samples were analyzed for a definitive diagnosis.

RESULTS

Adequate tissue samples were successfully obtained in all 11 cases. Of these, 7 patients (63.6%) were diagnosed with lymphoma, including subtypes such as extranodal marginal zone B-cell lymphoma, diffuse large B-cell lymphoma, and mantle cell lymphoma. Other diagnoses included IgG4-related ophthalmic disease (9.1%), and chronic inflammatory hyperplasia (27.3%). A small subcutaneous hematoma occurred in 1 patient (9.1%), which resolved without additional intervention.

CONCLUSION

CT-guided biopsy via the anterior approach is an effective technique for diagnosing orbital lymphoma. It is cost-effective, minimally invasive, allows for quicker recovery, and is associated with fewer adverse events compared to traditional surgical biopsy.