Gan to kagaku ryoho. Cancer & chemotherapy · 2004
[A case report of advanced cardiac cancer showing a complete response to TS-1 as neoadjuvant chemotherapy].
Клинический случайАннотация на английскомСтатьяНазвание и аннотация: Перевод пока не подготовлен
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Yamamoto Yasuhiro, Kino Yasuhisa, Ohara Kei, Onuma Sunao, Asai Keiko, Kobayashi Tatsuo, Kono Toru, Kasai Shinichi
Аннотация
A 69-year-old female had complaints of vomiting, appetite loss and feeling of pharyngeal obstruction. She was diagnosed with a 3'-shaped advanced cardiac cancer with esophageal invasion. A biopsy revealed poorly differentiated adenocarcinoma. The tumor was T3 (SE) N2, Stage IIIB indicating a poor prognosis. After informed consent, TS-1 was administrated as preoperative chemotherapy. Chemotherapy with TS-1 was very effective, and the tumor noticeably decreased. Next, total gastrectomy was performed. Histopathological findings revealed that the primary tumor and lymph node had become scarred and fibrous, indicating a complete response (Grade 3). In the future, TS-1 can be expected to display efficacy in neoadjuvant chemotherapy for patients with advanced gastric cancer who have poor prognoses.