The Journal of otolaryngology · 1996
Glottic microinvasive carcinoma: is it different from carcinoma in situ?
Сравнительное исследованиеСтатьяНазвание и аннотация: Перевод пока не подготовлен
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Nguyen C, Naghibzadeh B, Black M J, Rochon L, Shenouda G
Аннотация
OBJECTIVE: To determine the impact of different treatment modalities on the outcome of microinvasive carcinoma.
DESIGN: Retrospective review of patients presenting between 1976 and 1990.
SETTING: Fifteen patients with microinvasive carcinoma (MIC) of the glottic larynx treated at McGill University teaching hospitals.
METHODS: All patients had MIC involving the glottis confirmed pathologically. Nine patients (60%) had right vocal cord involvement, four (27%) had left vocal cord involvement, and two (13%) had involvement of both cords. Five patients (33%) were treated by stripping(S), three patients (20%) by stripping and radiotherapy (S + RT), and six patients (40%) by radiotherapy (RT) alone as the primary treatment. Only one patient underwent hemilaryngectomy.
RESULTS: With a median follow-up time of 63 months (range 20-208 months), the 15-year actuarial survival rate is 100% for all patients.
CONCLUSIONS: Surgery alone, RT alone, or S + RT is equally effective in treating MIC of the glottic larynx; however, single-modality therapy is preferred. The choice of treatment modality should be individualized for each patient.
DESIGN: Retrospective review of patients presenting between 1976 and 1990.
SETTING: Fifteen patients with microinvasive carcinoma (MIC) of the glottic larynx treated at McGill University teaching hospitals.
METHODS: All patients had MIC involving the glottis confirmed pathologically. Nine patients (60%) had right vocal cord involvement, four (27%) had left vocal cord involvement, and two (13%) had involvement of both cords. Five patients (33%) were treated by stripping(S), three patients (20%) by stripping and radiotherapy (S + RT), and six patients (40%) by radiotherapy (RT) alone as the primary treatment. Only one patient underwent hemilaryngectomy.
RESULTS: With a median follow-up time of 63 months (range 20-208 months), the 15-year actuarial survival rate is 100% for all patients.
CONCLUSIONS: Surgery alone, RT alone, or S + RT is equally effective in treating MIC of the glottic larynx; however, single-modality therapy is preferred. The choice of treatment modality should be individualized for each patient.