Head & neck · 2013
Oncocytic Schneiderian papillomas: Clinical behavior and outcomes of the endoscopic endonasal approach in 33 cases.
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Karligkiotis Apostolos, Bignami Maurizio, Terranova Paola, Gallo Stefania, Meloni Francesco, Padoan Giovanni, Lombardi Davide, Nicolai Piero, Castelnuovo Paolo
Аннотация
BACKGROUND: The purpose of this study was to evaluate the clinical behavior of oncocytic Schneiderian papillomas in relation to the rate of malignant transformation and recurrences and to report the long-term results of the endoscopic endonasal treatment.
METHODS: A retrospective analysis was carried out on patients with oncocytic papilloma, endoscopically managed over the past 20 years, at 2 university centers following a uniform policy.
RESULTS: Thirty-three patients were treated between November 1991 and December 2010. The mean follow-up period was 62 months. We observed 2 cases of persistence (6%) at the maxillary sinus level. Both of these patients underwent endoscopic surgical revision. Squamous cell carcinoma (SCC) was observed in 1 patient (3%).
CONCLUSION: The endonasal endoscopic technique proved to be a safe and effective approach for the treatment of oncocytic papillomas. An oncocytic papilloma is not to be considered a negative prognostic factor in terms of malignant transformation or recurrence.
METHODS: A retrospective analysis was carried out on patients with oncocytic papilloma, endoscopically managed over the past 20 years, at 2 university centers following a uniform policy.
RESULTS: Thirty-three patients were treated between November 1991 and December 2010. The mean follow-up period was 62 months. We observed 2 cases of persistence (6%) at the maxillary sinus level. Both of these patients underwent endoscopic surgical revision. Squamous cell carcinoma (SCC) was observed in 1 patient (3%).
CONCLUSION: The endonasal endoscopic technique proved to be a safe and effective approach for the treatment of oncocytic papillomas. An oncocytic papilloma is not to be considered a negative prognostic factor in terms of malignant transformation or recurrence.
Предметные рубрики MeSH
AdultAgedAged, 80 and overBiopsy, NeedleCell Transformation, NeoplasticEndoscopyFemaleFollow-Up StudiesHumansImmunohistochemistryItalyMagnetic Resonance ImagingMaleMiddle AgedNasal CavityNasal MucosaNeoplasm InvasivenessNeoplasm Recurrence, LocalNeoplasm StagingNose NeoplasmsOxyphil CellsPapilloma, InvertedParanasal Sinus NeoplasmsRetrospective StudiesRisk AssessmentSampling StudiesSurvival RateTomography, X-Ray ComputedTreatment Outcome