Future oncology (London, England) · 2018
Occupational exposure to fluoro-edenite and prevalence of anti-nuclear autoantibodies.
СтатьяНазвание и аннотация: Перевод пока не подготовлен
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Rapisarda Venerando, Loreto Carla, Castorina Sergio, Romano Gaetano, Garozzo Sebastiano Fabio, Musumeci Andrea, Migliore Marcello, Avola Roberto, Cinà Diana, Pomara Cristoforo, Ledda Caterina
Аннотация
An environmental contamination due to an asbestiform mineral fiber, fluoro-edenite (FE), caused a significantly increased mortality rate for malignant mesothelioma in Biancavilla, Italy. Exposure to fluoro-edenite has been associated with inflammatory processes as an early response to inhaled fibers. The aim was to explore prevalence of anti-nuclear autoantibodies (ANA) in a group of construction workers residing and working in the contaminated area. Prevalences for samples positive to ANA were 60% (n = 9) and 13% (n = 2), for exposed and nonexposed, respectively (p-value <0.05), the odds ratio was 9.75 (95% CI: 1.59-59.69). The significance of elevated ANAs in subjects exposed to fibers is unknown; additional studies may provide a better opportunity to establish a correlation between autoimmunity and environmental exposure.