Massive multilocular cystic leiomyoma of the uterus: an extreme example of hydropic degeneration.

A 49-year-old woman underwent laparotomy for an undiagnosed, extremely large abdominal mass. At surgery, this was discovered to be a uterine tumor and she was subjected to a subtotal hysterectomy. Pathologic examination of the uterus revealed a multilocular cystic mass containing over 18 L of fluid that was established on histology to be a markedly hydropic leiomyoma. This case describes a very uncommon growth pattern of leiomyoma of the uterus that has only been occasionally described previously. We propose the name multilocular, cystic leiomyoma for this variant.