Fa yi xue za zhi · 2006
[Forensic pathological significance of immunohistochemical study with CX43 in rats on early myocardial ischaemia].
Аннотация на английскомСтатьяНазвание и аннотация: Перевод пока не подготовлен
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Jin Li-fang, Chen Ming-fang, Zheng Qiang, Xu Jing-yao, Shen Yong-hao, Zhu You-fa
Аннотация
OBJECTIVE: To explore one of evidence for pathologic diagnosis of early myocardial ischaemia.
METHODS: Rats were ligated of the left coronary artery according to a previously documented technique, and heart tissue was sampled at different ischaemia time. The expression of CX43 in myocardial cell was detected by Immunohistochemistry.
RESULTS: It is showed that the distribution and amount of CX43 positive staining in each group of the myocardial ischaemia was different from that of the control group.
CONCLUSION: The changes of CX43 detected by Immunohistochemical methods may be helpful for the diagnosis of early myocardial ischaemia, but further pathologic investigation and research is necessary.
METHODS: Rats were ligated of the left coronary artery according to a previously documented technique, and heart tissue was sampled at different ischaemia time. The expression of CX43 in myocardial cell was detected by Immunohistochemistry.
RESULTS: It is showed that the distribution and amount of CX43 positive staining in each group of the myocardial ischaemia was different from that of the control group.
CONCLUSION: The changes of CX43 detected by Immunohistochemical methods may be helpful for the diagnosis of early myocardial ischaemia, but further pathologic investigation and research is necessary.