Медицинская библиотека · Fa yi xue za zhi · 2006

[Forensic pathological significance of immunohistochemical study with CX43 in rats on early myocardial ischaemia].

Jin Li-fang, Chen Ming-fang, Zheng Qiang, Xu Jing-yao, Shen Yong-hao, Zhu You-fa

Аннотация на английскомСтатьяПеревод пока не подготовлен

Аннотация

OBJECTIVE

To explore one of evidence for pathologic diagnosis of early myocardial ischaemia.

METHODS

Rats were ligated of the left coronary artery according to a previously documented technique, and heart tissue was sampled at different ischaemia time. The expression of CX43 in myocardial cell was detected by Immunohistochemistry.

RESULTS

It is showed that the distribution and amount of CX43 positive staining in each group of the myocardial ischaemia was different from that of the control group.

CONCLUSION

The changes of CX43 detected by Immunohistochemical methods may be helpful for the diagnosis of early myocardial ischaemia, but further pathologic investigation and research is necessary.

Для цитирования: Jin Li-fang, Chen Ming-fang, Zheng Qiang, Xu Jing-yao, Shen Yong-hao, Zhu You-fa. [Forensic pathological significance of immunohistochemical study with CX43 in rats on early myocardial ischaemia].. Fa yi xue za zhi. 2006.

Предметные рубрики MeSH

Animals Connexin 43 Disease Models, Animal Female Forensic Pathology Immunohistochemistry Male Myocardial Ischemia Myocytes, Cardiac Myometrium Random Allocation Rats Rats, Sprague-Dawley Staining and Labeling Time Factors Tissue Distribution

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