Immunobiology of the expanded T cells in T-cell leukemia and T-gamma lymphocytosis.

A review is presented of functional studies performed with the expanded T cells in Sézary syndrome, T-cell chronic lymphocytic leukemia (T-CLL), T-prolymphocytic leukemia (T-PLL), adult T-cell leukemia lymphoma (ATLL), T-cell acute lymphoblastic leukemia (T-ALL) and T gamma lymphocytosis. The immunological and clinical relevance of immunological studies of functional properties of T-cell expansions is discussed.