Obesity surgery · 2021
Metabolic Effects of Endoscopic Duodenal Mucosal Resurfacing: a Systematic Review and Meta-analysis.
СтатьяМетаанализСистематический обзорНазвание и аннотация: Перевод пока не подготовлен
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de Oliveira Guilherme Henrique Peixoto, de Moura Diogo Turiani Hourneaux, Funari Mateus Pereira, McCarty Thomas R, Ribeiro Igor Braga, Bernardo Wanderley Marques, Sagae Vitor Massaro Takamatsu, Freitas João Remi, Souza Gabriel Mayo de Vieira, de Moura Eduardo Guimarães Hourneaux
Аннотация
Duodenal mucosal resurfacing (DMR) is an innovative endoscopic bariatric and metabolic therapy (EBMT) emerging in recent years. It uses the duodenum to achieve better glycemic and weight control. This study aimed to evaluate in a critical and systematic way the metabolic effects of this procedure. Electronic searches were performed evaluating the DMR procedure based on predefined inclusion and exclusion criteria. Changes in measured outcomes were evaluated using random-effects models by computing weighted mean differences (MD) and corresponding 95% CIs between pre-and post-procedure metabolic characteristics. Four studies were selected for qualitative and quantitative analysis. DMR demonstrated beneficial glycemic and hepatic metabolic effects among patients with non-insulin dependent type 2 diabetes (T2D) at 3 and 6 months post-procedure.