Annals of surgery · 2025
Outcomes of Minimally Invasive Versus Open Gastrectomy for Gastric Cancer Surgery With Curative Intent: A Population-based Cohort Study.
СтатьяСравнительное исследованиеМногоцентровое исследованиеПоддержка исследования: вне правительства СШАНазвание и аннотация: Перевод пока не подготовлен
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Garsot Elisenda, Sentí Sara, Salvador Helena, Eizaguirre Emma, Estremiana Fernando, Castro Sandra, Miranda Coro, Reka Lorena, Leturio Saioa, Codony Clara, Momblán Dulce, Gobbini Yanina, Luna Alexis, Fernández-Ananin Sonia, Sendiño Patricia, Clavell Arantxa, Olona Carles, Aldeano Aurora, Rodríguez-Santiago Joaquín, Hermoso Judith, Güell Mercè, Sánchez-Cano Juan J, Pulido Laura, García-Tejero Aitana, Dal Cero Mariagiulia, Gimeno Marta, Pallarès Natalia, Grande Luis, Pera Manuel, the Spanish EURECCA Esophagogastric Cancer Group
Аннотация
OBJECTIVE: To compare postoperative events and oncologic results between minimally invasive gastrectomy (MIG) and open gastrectomy (OG) in gastric cancer surgery.
BACKGROUND: Evidence of the short-term and long-term results of MIG is still limited.
METHODS: A population-based cohort study included all patients undergoing elective gastric cancer resection with curative intent between 2014 and 2021 across 39 centers belonging to the EURECCA Spanish Registry. Postoperative complications, 90-day mortality, and 5-year overall survival (OS) and disease-free survival (DFS) were analyzed in the groups of MIG and OG using propensity score matching (1:1). Subtotal gastrectomy (SG) versus total gastrectomy (TG) was also assessed.
RESULTS: A total of 1333 matched-pair patients were included. The use of MIG increased significantly from 2017. The comparison of OG and MIG showed similar results for overall complications (47.4% vs 44.7%), major complications (19.1 vs 18.2%), 90-day mortality (4.4% vs 3.2%), and failure to rescue (23.1% vs 17.3%), but the MIG group showed significantly shorter median length of hospitalization ( P < 0.001) in the overall study population (8 vs 10 days) as well as in the subgroups of SG (7 vs 8 days) and TG (10 vs 11 days), and higher ≥ 15 nodes retrieval (84.2% vs 78.8%, P < 0.001). Anastomotic leakage after TG was high (about 17%) and did not differ between surgical approaches. Also, MIG and OG showed similar 5-year OS (62% vs 64.6%) and DFS (58.5% vs 56.5%).
CONCLUSIONS: The implementation of MIG did not increase complications and showed similar oncologic outcomes as compared with OG.
BACKGROUND: Evidence of the short-term and long-term results of MIG is still limited.
METHODS: A population-based cohort study included all patients undergoing elective gastric cancer resection with curative intent between 2014 and 2021 across 39 centers belonging to the EURECCA Spanish Registry. Postoperative complications, 90-day mortality, and 5-year overall survival (OS) and disease-free survival (DFS) were analyzed in the groups of MIG and OG using propensity score matching (1:1). Subtotal gastrectomy (SG) versus total gastrectomy (TG) was also assessed.
RESULTS: A total of 1333 matched-pair patients were included. The use of MIG increased significantly from 2017. The comparison of OG and MIG showed similar results for overall complications (47.4% vs 44.7%), major complications (19.1 vs 18.2%), 90-day mortality (4.4% vs 3.2%), and failure to rescue (23.1% vs 17.3%), but the MIG group showed significantly shorter median length of hospitalization ( P < 0.001) in the overall study population (8 vs 10 days) as well as in the subgroups of SG (7 vs 8 days) and TG (10 vs 11 days), and higher ≥ 15 nodes retrieval (84.2% vs 78.8%, P < 0.001). Anastomotic leakage after TG was high (about 17%) and did not differ between surgical approaches. Also, MIG and OG showed similar 5-year OS (62% vs 64.6%) and DFS (58.5% vs 56.5%).
CONCLUSIONS: The implementation of MIG did not increase complications and showed similar oncologic outcomes as compared with OG.