Morphological changes of the hypophysis-adrenal system (HAS) in albino rats with experimental gastric ulcers, under the influence of aeroionotherapy (AIT).

The authors followed up certain changes occurring at the level of the hypophysis-adrenal axis, during the development of experimental ulcers induced by pylorus ligature in rats treated with negative air ions. Previous experiments have shown that negative aeroionotherapy had a favourable influence on the prevention and evolution of gastric ulcers. The results of the present experiment showed that, under the influence of aeroionotherapy, the number of gastric ulcers/animal, and the relative weight of the adenohypophysis and of the adrenals glands decreased; the width of the fascicular zone of the adrenal cortex, and the volume of the cell nuclei in this fascicular zone also decreased.