[A case of advanced colon cancer with para-aortic lymph node metastasis responding greatly to treatment by adjuvant chemotherapy of low-dose CPT-11 on an outpatient basis].

We administered an adjuvant chemotherapy of a bi-weekly low-dose CPT-11 + 5-FU on an outpatient basis to a patient with advanced sigmoid colon cancer and para-aortic lymph node metastasis. After 3 months, tumor markers fell to normal levels and the regression rate in the lymph node was over 80%. Throughout the period of treatment, there were no side effects, and there was no sign of recurrence for 6 months. In conclusion, we consider that with low-dose CPT-11 + 5-FU chemotherapy on an outpatient basis, the patient can maintain a high quality of life and show a massive effect, and that this regimen can be used as a first-line chemotherapy for advanced colon cancer.