Human pathology · 2003
Invasive thymoma with paraneoplastic retinopathy.
Клинический случайСтатьяНазвание и аннотация: Перевод пока не подготовлен
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Yamada Gen, Ohguro Hiroshi, Aketa Katsuyuki, Itoh Takayuki, Shijubo Noriharu, Takahashi Hiroki, Fujiwara Osamutaro, Satoh Masaaki, Ohtsuka Kenji, Abe Shosaku
Аннотация
A 60-year-old man was admitted for progressive visual loss in both eyes. He was diagnosed with retinopathy and chest computed tomography revealed an invasive thymoma. In western blot analysis, serum autoantibodies against recoverin, photoreceptor-specific calcium-binding protein, and heat shock cognate protein 70 which were identified as the cause of cancer-associated retinopathy (CAR). Immunofluorescence staining showed that thymoma cells also expressed recoverin. These observations strongly suggested that similar pathogenesis of CAR was involved in the presented case.
Предметные рубрики MeSH
Biomarkers, TumorBlotting, WesternCalcium-Binding ProteinsEye ProteinsFluorescein-5-isothiocyanateFluorescent Antibody Technique, IndirectHippocalcinHumansLipoproteinsMaleMiddle AgedNeoplasm InvasivenessNerve Tissue ProteinsParaneoplastic SyndromesRecoverinRetinal DiseasesThymectomyThymomaThymus NeoplasmsTreatment Outcome