Journal of parasitology research · 2026
Seroprevalence of Strongyloides stercoralis Infection and Its Risk Factors in Pregnant Women Referred to Al-Zahra Hospital in Guilan Province, North Part of Iran: A Cross-Sectional Study From 2024 to 2025.
СтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Sorouri Majd Mahdieh, Kia Eshrat Beigom, Sharami Seyedeh Hajar, Mohebali Mehdi, Jafari Azadeh, Latifi Roya, Fakhrieh-Kashan Zohreh
Аннотация
BACKGROUND: In immunocompromised individuals, strongyloidiasis may progress to hyperinfection syndrome or disseminated disease. To date, the death of a pregnant woman infected with Strongyloides stercoralis has been reported. Chronic cases carry a risk of malnutrition, especially among vulnerable populations like pregnant women and children. Pregnancy-related immunosuppression increases susceptibility to severe strongyloidiasis. This study assesses strongyloidiasis seroprevalence in pregnant women at Al-Zahra Hospital, Guilan Province.
MATERIALS AND METHODS: This cross-sectional study (September 2024 to February 2025) randomly selected 384 pregnant women referred to Al-Zahra Hospital, Rasht. After consent, blood (all) and permitted stool samples plus symptom questionnaires were collected. Serum was tested for anti-S. stercoralis IgG antibodies using ELISA (NovaLisa). Stool underwent parasitological examination (direct smear, formalin-ethyl acetate concentration method, and nutrient agar plate culture [APC]). SPSS v25 analyzed data using Fisher's exact test.
RESULTS: The study enrolled pregnant women (gestational age: 1-8 months) aged 15-48 years. The seroprevalence of strongyloidiasis (anti-S. stercoralis IgG antibodies) was 2.6%. Six of these individuals, who provided stool samples, also tested positive by parasitological examination. No significant associations (p > 0.05) were observed between infection and factors including vegetable washing practices, residential location (urban/rural), education level, occupational exposure, soil contact, clinical symptoms, animal contact, or hypereosinophilia. However, a significant association (p < 0.05) was identified between strongyloidiasis and underlying conditions, with gestational diabetes present in 30% of patients.
CONCLUSION: The overlap of gastrointestinal, respiratory, and hematological symptoms with pregnancy contributes to the underdiagnosis of strongyloidiasis. Early respiratory symptoms are hormonally driven, whereas persistent later symptoms suggest infection (50% strongyloidiasis cases here). Preconception S. stercoralis serology and hygiene/animal-contact education are recommended.
MATERIALS AND METHODS: This cross-sectional study (September 2024 to February 2025) randomly selected 384 pregnant women referred to Al-Zahra Hospital, Rasht. After consent, blood (all) and permitted stool samples plus symptom questionnaires were collected. Serum was tested for anti-S. stercoralis IgG antibodies using ELISA (NovaLisa). Stool underwent parasitological examination (direct smear, formalin-ethyl acetate concentration method, and nutrient agar plate culture [APC]). SPSS v25 analyzed data using Fisher's exact test.
RESULTS: The study enrolled pregnant women (gestational age: 1-8 months) aged 15-48 years. The seroprevalence of strongyloidiasis (anti-S. stercoralis IgG antibodies) was 2.6%. Six of these individuals, who provided stool samples, also tested positive by parasitological examination. No significant associations (p > 0.05) were observed between infection and factors including vegetable washing practices, residential location (urban/rural), education level, occupational exposure, soil contact, clinical symptoms, animal contact, or hypereosinophilia. However, a significant association (p < 0.05) was identified between strongyloidiasis and underlying conditions, with gestational diabetes present in 30% of patients.
CONCLUSION: The overlap of gastrointestinal, respiratory, and hematological symptoms with pregnancy contributes to the underdiagnosis of strongyloidiasis. Early respiratory symptoms are hormonally driven, whereas persistent later symptoms suggest infection (50% strongyloidiasis cases here). Preconception S. stercoralis serology and hygiene/animal-contact education are recommended.