Prevalence of glucose-6-phosphate dehydrogenase deficiency in neonates in Egypt.

BACKGROUND

Glucose-6-phosphate dehydrogenase (G6PD) deficiency is an X-linked disorder which causes neonatal jaundice in most cases, and under certain conditions, can cause a spectrum of hemolytic manifestations.

OBJECTIVE

To determine the local prevalence of G6PD deficiency in newborns.

DESIGN

Cross-sectional.

SETTING

University hospital.

METHODS

Infants born during 2015 were prospectively screened for G6PD deficiency. Dried blood spot samples on filter paper were collected in collaboration with the central laboratories of the Ministry of Health. Quantitative measurement of G6PD enzyme activity was measured from the blood samples using fluorometric analysis. A value.