Acta radiologica (Stockholm, Sweden : 1987) · 2013
High impact of FDG-PET/CT in diagnostic strategies for ovarian cancer.
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Zytoon Ashraf Anas, Murakami Koji, Eid Hazem, El-Gammal Mahmoud
Аннотация
BACKGROUND: Ovarian cancer has the highest mortality of all gynecologic malignancies. FDG-PET/CT was proven to be accurate for identification of primary ovarian tumors, regional lymph nodes, and distant metastases.
PURPOSE: To evaluate ovarian masses at FDG-PET/CT in correlation with histopathologic findings.
MATERIAL AND METHODS: Ninety-eight patients underwent whole body FDG-PET/CT examination. Eighty-six patients with primary ovarian cancer and 12 patients with metastatic disease to the ovaries were included.
RESULTS: PET/CT imaging was true-positive in 87/94 patients with malignant tumors. In 4/4 patients with benign tumors, PET/CT results were true-negative, with sensitivity of 92.6%, specificity 100%, total test accuracy 92.9%. Fifty-seven patients were diagnosed as stage IV ovarian cancer with distant metastasis.
CONCLUSION: The anatomical/functional examination by FDG-PET/CT was proven to be valuable in increasing the diagnostic accuracy that can help improve patient management.
PURPOSE: To evaluate ovarian masses at FDG-PET/CT in correlation with histopathologic findings.
MATERIAL AND METHODS: Ninety-eight patients underwent whole body FDG-PET/CT examination. Eighty-six patients with primary ovarian cancer and 12 patients with metastatic disease to the ovaries were included.
RESULTS: PET/CT imaging was true-positive in 87/94 patients with malignant tumors. In 4/4 patients with benign tumors, PET/CT results were true-negative, with sensitivity of 92.6%, specificity 100%, total test accuracy 92.9%. Fifty-seven patients were diagnosed as stage IV ovarian cancer with distant metastasis.
CONCLUSION: The anatomical/functional examination by FDG-PET/CT was proven to be valuable in increasing the diagnostic accuracy that can help improve patient management.
Предметные рубрики MeSH
AdolescentAdultAgedAged, 80 and overBiomarkers, TumorFemaleFluorodeoxyglucose F18HumansImage Interpretation, Computer-AssistedLymphatic MetastasisMiddle AgedMultimodal ImagingOvarian NeoplasmsPositron-Emission TomographyProspective StudiesROC CurveRadiopharmaceuticalsSensitivity and SpecificityStatistics, NonparametricTomography, X-Ray Computed