BJOG : an international journal of obstetrics and gynaecology · 2012
Image assessment of cervical dimensions after LLETZ: a prospective observational study.
Сравнительное исследованиеОценочное исследованиеСтатьяПоддержка исследования: вне правительства СШАНазвание и аннотация: Перевод пока не подготовлен
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Carcopino X, Maycock J A, Mancini J, Jeffers M, Farrar K, Martin M, Khalid S, Prendiville W
Аннотация
OBJECTIVE: To assess the impact of large loop excision of the transformation zone (LLETZ) for cervical intraepithelial neoplasia (CIN) on cervical morphology as assessed by three-dimensional ultrasound.
DESIGN: Prospective observational study.
SETTING: University Hospital in Dublin.
POPULATION: Women with CIN who underwent an LLETZ procedure.
METHODS: All 106 participants had a three-dimensional transvaginal ultrasound scan (3DTVS) performed immediately before and 6 months after LLETZ. The excised LLETZ specimen dimensions were also recorded. Blind analysis of the images was performed. The volume of the uterus and cervix was documented.
MAIN OUTCOME MEASURES: The relationship between the extirpated LLETZ dimensions and subsequent cervical and uterine biometry, as assessed by 3DTVS.
RESULTS: LLETZ induced a statistically significant reduction in both the length (mean, -0.46 cm; P < 0.001) and the volume (-6.12 cm(3) ; P < 0.001) of the uterus, and in the volume of the cervix (-1.60 cm(3) ; P < 0.001). The volume of the excised specimen had a significant impact on the reduction of the length of the uterus (β, -0.038; P = 0.012), the volume of the uterus (β, -0.791; P = 0.036) and the volume of the cervix (β, -0.121; P = 0.046). The circumference of the excised specimen appeared to have a significant impact on the length (β, -0.016; 95% CI, -0.028 to -0.003; P = 0.013) and volume (β, -0.413; 95% CI, -0.719 to -0.107; P = 0.009) of the uterus 6 months after LLETZ.
CONCLUSIONS: The volume of tissue removed at LLETZ is related to the subsequent cervical volume, as well as the uterine length and volume, 6 months after the procedure.
DESIGN: Prospective observational study.
SETTING: University Hospital in Dublin.
POPULATION: Women with CIN who underwent an LLETZ procedure.
METHODS: All 106 participants had a three-dimensional transvaginal ultrasound scan (3DTVS) performed immediately before and 6 months after LLETZ. The excised LLETZ specimen dimensions were also recorded. Blind analysis of the images was performed. The volume of the uterus and cervix was documented.
MAIN OUTCOME MEASURES: The relationship between the extirpated LLETZ dimensions and subsequent cervical and uterine biometry, as assessed by 3DTVS.
RESULTS: LLETZ induced a statistically significant reduction in both the length (mean, -0.46 cm; P < 0.001) and the volume (-6.12 cm(3) ; P < 0.001) of the uterus, and in the volume of the cervix (-1.60 cm(3) ; P < 0.001). The volume of the excised specimen had a significant impact on the reduction of the length of the uterus (β, -0.038; P = 0.012), the volume of the uterus (β, -0.791; P = 0.036) and the volume of the cervix (β, -0.121; P = 0.046). The circumference of the excised specimen appeared to have a significant impact on the length (β, -0.016; 95% CI, -0.028 to -0.003; P = 0.013) and volume (β, -0.413; 95% CI, -0.719 to -0.107; P = 0.009) of the uterus 6 months after LLETZ.
CONCLUSIONS: The volume of tissue removed at LLETZ is related to the subsequent cervical volume, as well as the uterine length and volume, 6 months after the procedure.