Future oncology (London, England) · 2022
Effect of lateral lymph nodes without malignant characteristics on the prognosis of patients with rectal cancer.
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Zhang Chenghai, Cui Ming, Xing Jiadi, Yang Hong, Yao Zhendan, Zhang Nan, Tan Fei, Liu Maoxing, Xu Kai, Su Xiangqian
Аннотация
Background: Lateral lymph node (LLN) metastasis is a poor prognostic factor for rectal cancer patients. However, the effect of LLNs without malignant characteristics on the prognosis of rectal cancer patients has been uncertain. Methods: Consecutive patients who underwent laparoscopic-assisted low anterior resection were included. Patients with MRI-detected LLNs, but without malignant characteristics, were compared with patients with no MRI-detected LLNs. Results: The local recurrence rate was higher in the LLN-present group than in the LLN-absent group (9.8% vs 2.5%; p = 0.056). The overall survival of patients with no MRI-detected LLNs was significantly better than that of patients with MRI-detected LLNs (p = 0.021). Conclusion: The presence of LLNs, even without malignant features, may lead to worse local control and overall survival.