Медицинская библиотека · Future oncology (London, England) · 2022

Effect of lateral lymph nodes without malignant characteristics on the prognosis of patients with rectal cancer.

Zhang Chenghai, Cui Ming, Xing Jiadi, Yang Hong, Yao Zhendan, Zhang Nan, Tan Fei, Liu Maoxing, Xu Kai, Su Xiangqian

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Аннотация

Background

Lateral lymph node (LLN) metastasis is a poor prognostic factor for rectal cancer patients. However, the effect of LLNs without malignant characteristics on the prognosis of rectal cancer patients has been uncertain.

Methods

Consecutive patients who underwent laparoscopic-assisted low anterior resection were included. Patients with MRI-detected LLNs, but without malignant characteristics, were compared with patients with no MRI-detected LLNs.

Results

The local recurrence rate was higher in the LLN-present group than in the LLN-absent group (9.8% vs 2.5%; p = 0.056). The overall survival of patients with no MRI-detected LLNs was significantly better than that of patients with MRI-detected LLNs (p = 0.021).

Conclusion

The presence of LLNs, even without malignant features, may lead to worse local control and overall survival.

Для цитирования: Zhang Chenghai, Cui Ming, Xing Jiadi, Yang Hong, Yao Zhendan, Zhang Nan, Tan Fei, Liu Maoxing, Xu Kai, Su Xiangqian. Effect of lateral lymph nodes without malignant characteristics on the prognosis of patients with rectal cancer.. Future oncology (London, England). 2022. DOI: 10.2217/fon-2022-0476.

Предметные рубрики MeSH

Humans Lymph Node Excision Rectal Neoplasms Lymph Nodes Lymphatic Metastasis Prognosis Neoplasm Recurrence, Local Retrospective Studies Neoplasm Staging

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