Fertility and sterility · 2006
Embryos generated using testicular spermatozoa have higher developmental potential than those obtained using epididymal spermatozoa in men with obstructive azoospermia.
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Dozortsev Dmitri, Neme Rosa, Diamond Michael P, Abdelmassih Soraya, Abdelmassih Vicente, Oliveira Flavio, Abdelmassih Roger
Аннотация
OBJECTIVE: To determine whether the injection of testicular spermatozoa results in more viable embryos (higher implantation rate) than injection of epididymal spermatozoa in cases of obstructive azoospermia.
DESIGN: Retrospective analysis of 265 cases of testicular sperm aspiration (TESA) and percutaneous sperm aspiration (PESA), including 185 cases of obstructive azoospermia.
SETTING: Private Infertility clinic.
PATIENT(S): None, charts review.
INTERVENTION(S): None, charts review.
MAIN OUTCOME MEASURE(S): Clinical pregnancy rate (PR), implantation rate.
RESULT(S): Although fertilization rates were higher in the PESA group, implantation rates were significantly better in the TESA group. There was also a trend to higher ongoing PR and lower miscarriage rates in TESA cases.
CONCLUSION(S): In cases of obstructive azoospermia, embryos generated using testicular spermatozoa have higher developmental potential than those obtained using epididymal spermatozoa.
DESIGN: Retrospective analysis of 265 cases of testicular sperm aspiration (TESA) and percutaneous sperm aspiration (PESA), including 185 cases of obstructive azoospermia.
SETTING: Private Infertility clinic.
PATIENT(S): None, charts review.
INTERVENTION(S): None, charts review.
MAIN OUTCOME MEASURE(S): Clinical pregnancy rate (PR), implantation rate.
RESULT(S): Although fertilization rates were higher in the PESA group, implantation rates were significantly better in the TESA group. There was also a trend to higher ongoing PR and lower miscarriage rates in TESA cases.
CONCLUSION(S): In cases of obstructive azoospermia, embryos generated using testicular spermatozoa have higher developmental potential than those obtained using epididymal spermatozoa.