Prospective randomized comparison of simultaneous and sequential bilateral photorefractive keratectomy for the correction of myopia.

BACKGROUND AND

OBJECTIVE

To evaluate the efficacy and safety of simultaneous bilateral photorefractive keratectomy (PRK).

PATIENTS AND

METHODS

There were 52 patients (104 eyes) with myopia less than -6 diopters entered in this prospective trial and randomized to simultaneous or sequential bilateral PRK. Main outcome measures were uncorrected visual acuity (UCVA), percentage of eyes within +/-0.5 D of attempted outcome, present pain intensity (PPI) and total pain rating index (PRI(R)T) scores resulting from McGill the Pain Questionnaire, subjective symptoms, haze, and patient satisfaction. Follow-up extended to 14 months.

RESULTS

There was no significant difference in UCVA (P=0.996) and percentage of eyes within +/-0.5 D of attempted correction (P=0.932). Present pain intensity and PRI(R)T scores were significantly higher in the sequential group (P=0.037; P=0.034). The percentage of satisfied patients after bilateral PRK was significantly higher in the simultaneous group (P=0.036).

CONCLUSIONS

Simultaneous bilateral PRK was safe and effective, without any significant difference from sequential treatment.