Cancer · 1992
Leptomeningeal myelomatosis presenting with mental status changes and other neurologic findings.
Клинический случайСтатьяОбзорНазвание и аннотация: Перевод пока не подготовлен
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Leifer D, Grabowski T, Simonian N, Demirjian Z N
Аннотация
BACKGROUND: Leptomeningeal myelomatosis is a rare complication of multiple myeloma.
METHODS: The authors identified and studied three patients with leptomeningeal myelomatosis and reviewed previous case reports of this condition.
RESULTS: The patients described here had intermittent abnormalities in mental status or cranial nerve and brain stem abnormalities. Two of the patients responded dramatically, though transiently, to treatment. In one patient, the clinical findings correlated with lesions visualized by gadolinium-enhanced magnetic resonance imaging.
CONCLUSIONS: These patients are typical of those reported previously. Patients with leptomeningeal myelomatosis often have a good response to treatment initially, but long-term survival is rare.
METHODS: The authors identified and studied three patients with leptomeningeal myelomatosis and reviewed previous case reports of this condition.
RESULTS: The patients described here had intermittent abnormalities in mental status or cranial nerve and brain stem abnormalities. Two of the patients responded dramatically, though transiently, to treatment. In one patient, the clinical findings correlated with lesions visualized by gadolinium-enhanced magnetic resonance imaging.
CONCLUSIONS: These patients are typical of those reported previously. Patients with leptomeningeal myelomatosis often have a good response to treatment initially, but long-term survival is rare.