European journal of gynaecological oncology · 2012
The role of surgery in patients with advanced gynaecological cancers participating in phase I clinical trials.
Клинический случайСтатьяПоддержка исследования: вне правительства СШАНазвание и аннотация: Перевод пока не подготовлен
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Vitfell-Pedersen J, Yap T A, Moreno V, Baird R D, Khan A Z, Barton D P J, Kaye S B
Аннотация
OBJECTIVE: While gynaecological cancer patients who participate in Phase I clinical trials are not routinely considered for elective surgery because of a short life expectancy, this should not be overlooked in carefully selected responding patients.
METHODS/RESULTS: We describe two cases of patients with different gynaecological cancers, who received treatment within separate phase I trials, and who then proceeded to surgical resection of their cancers, resulting in complete remission.
CONCLUSION: Surgery, when feasible, should be taken into consideration as a potential management option, even when patients are receiving treatment within a phase I trial.
METHODS/RESULTS: We describe two cases of patients with different gynaecological cancers, who received treatment within separate phase I trials, and who then proceeded to surgical resection of their cancers, resulting in complete remission.
CONCLUSION: Surgery, when feasible, should be taken into consideration as a potential management option, even when patients are receiving treatment within a phase I trial.
Предметные рубрики MeSH
Adenocarcinoma, PapillaryAdultAfatinibAgedAntibodies, Monoclonal, HumanizedAntineoplastic AgentsAntineoplastic Combined Chemotherapy ProtocolsBevacizumabCarcinoma, Squamous CellClinical Trials, Phase I as TopicFemaleHumansLiver NeoplasmsLung NeoplasmsLymph Node ExcisionLymphatic MetastasisOvarian NeoplasmsPaclitaxelPelvic NeoplasmsPhthalazinesPiperazinesQuinazolinesUterine Cervical Neoplasms