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DOI 10.1017/s0022215119001725

Медицинская библиотека · The Journal of laryngology and otology · 2019

Elective neck dissection for the node-negative neck during salvage laryngectomy: an analysis of survival outcomes and complication rates.

Gouzos M, Dale O, Sethi N, Foreman A, Krishnan S, Hodge J C

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Аннотация

OBJECTIVES

This study aimed to evaluate the effect of neck dissection on survival and complication rates in patients with no clinical or radiological evidence of cervical nodal disease (N0) undergoing salvage laryngectomy.

METHODS

A retrospective study was conducted of patients with squamous cell carcinoma of the larynx following primary radiotherapy that required salvage laryngectomy. Disease-free and overall survival rates were compared over three years using Kaplan-Meier analysis. Pharyngocutaneous fistula rate, hospitalisation length and the requirement for further surgical intervention were also compared across cohorts.

RESULTS

Twenty-three cases met the inclusion criteria (17 neck dissections, 6 undissected). No significant differences in survival outcomes were identified. One patient who underwent neck dissection for advanced, recurrent transglottic squamous cell carcinoma showed evidence of occult lymph node metastases. Fistula rates did not differ significantly between dissected and non-dissected groups; however, two patients required surgical repair of post-operative pharyngocutaneous fistula following neck dissection.

CONCLUSION

In this study, elective neck dissection did not appear to alter survival outcomes or complication rates during salvage laryngectomy. Given the small but significant risk of occult neck metastases, its true value remains unclear.

Для цитирования: Gouzos M, Dale O, Sethi N, Foreman A, Krishnan S, Hodge J C. Elective neck dissection for the node-negative neck during salvage laryngectomy: an analysis of survival outcomes and complication rates.. The Journal of laryngology and otology. 2019. DOI: 10.1017/s0022215119001725.
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