Automated screening of gynecologic cytology: a comparison of results.

OBJECTIVE

To compare the results among conventional gynecologic cytology liquid-based cytology and manual screening and liquid-based cytology automatically screened.

STUDY

DESIGN

The results of 53,311 cervicovaginal samples, corresponding to 53,311 women of Barcelona, Spain are reviewed. The cases are subdivided into 19,742 conventional cervicovaginal samples; 17,596 liquid-based cytology, manually screened samples; and 15,973 liquid-based automated-screened samples.

RESULTS

The automated screening increases the atypical squamous cells of undetermined significance and low-grade squamous intraepithelial lesion detection, in respect to liquid-based, manual screening and conventional cytology. In the follow-up, automated screening increases the diagnosis of squamous intraepithelial lesion (low-grade squamous intraepithelial lesion and high-grade squamous intraepithelial lesion).

CONCLUSION

Automated screening increases detection of all categories and increases the specificity for high-grade squamous intraepithelial lesion.