Retina (Philadelphia, Pa.) · 2025
Autologous retinal graft surgery for refractory macular holes without postoperative head positioning.
СтатьяНазвание и аннотация: Перевод пока не подготовлен
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Shcolnik Eilon, Shoham-Hazon Nir, Tuli Raman, Schlesinger Mor, Ben Zaken Shalhevet Goldfeather, Kozlov Yuval, Berco Efraim
Аннотация
PURPOSE: To evaluate the efficacy of autologous retinal graft (ARG) surgery using a novel technique of Viscoat as a graft adherent and stabilizer for large, refractory macular holes (MHs) without postoperative face-down positioning.
METHODS: This retrospective interventional case series included 13 patients with refractory MHs who underwent ARG surgery. The surgical technique involved retinal graft placement stabilized with Viscoat, without postoperative positioning. Preoperative, 6 months and 12 months postoperative outcomes, including MH closure rates and visual acuity (VA) were analyzed.
RESULTS: Pre-op mean MH size was 821.69 ± 180.65 µm (range: 563-1200 µm). Anatomical closure was achieved in 76.9% (10/13) of cases. Median VA improved from 1.7 logMAR (20/1000) preoperatively to 1.3 logMAR (20/400) at 6 months and at 12 months postoperatively, although this change was not statistically significant (p = 0.106 and p = 0.311 respectively). No major complications were reported. Larger MH size and chronicity might limit functional improvement despite successful closure.
CONCLUSION: This is the first study to demonstrate that ARG surgery with Viscoat can achieve high closure rates without postoperative head positioning. The technique offers a patient-friendly alternative for refractory MH management, reducing postoperative burden while maintaining promising anatomical outcomes. Further studies with larger cohorts are warranted to validate these findings.
METHODS: This retrospective interventional case series included 13 patients with refractory MHs who underwent ARG surgery. The surgical technique involved retinal graft placement stabilized with Viscoat, without postoperative positioning. Preoperative, 6 months and 12 months postoperative outcomes, including MH closure rates and visual acuity (VA) were analyzed.
RESULTS: Pre-op mean MH size was 821.69 ± 180.65 µm (range: 563-1200 µm). Anatomical closure was achieved in 76.9% (10/13) of cases. Median VA improved from 1.7 logMAR (20/1000) preoperatively to 1.3 logMAR (20/400) at 6 months and at 12 months postoperatively, although this change was not statistically significant (p = 0.106 and p = 0.311 respectively). No major complications were reported. Larger MH size and chronicity might limit functional improvement despite successful closure.
CONCLUSION: This is the first study to demonstrate that ARG surgery with Viscoat can achieve high closure rates without postoperative head positioning. The technique offers a patient-friendly alternative for refractory MH management, reducing postoperative burden while maintaining promising anatomical outcomes. Further studies with larger cohorts are warranted to validate these findings.